泌尿系感染病原菌的分布及抗菌素耐药性分析

Drug resistance and distribution of 476 strains of pathogenic bacteria leading to urological infection

目的为了探讨泌尿系感染病原菌的种类及其耐药性。方法用普通培养法检测706例泌尿系感染患者的新鲜中段尿标本,K—B法进行药敏试验。结果706例受检标本分离出致病菌476株,主要菌群有大肠杆菌、粪肠球菌以及葡萄球菌、克雷伯杆菌、变形杆菌等。除11株真菌外,其余465株致病菌对氨苄青霉素和青霉素的耐药率最高,分别达70%和76%;亚氨培南、万古霉素最低分别为2%和0%,其次是丁氨卡那为10%。结论泌尿系感染病原菌的耐药性监测,对指导临床治疗具有重要意义。

To study the type of pathogenic bacteria leading to urinary tract infections (UTI) and its drug resistance. 706 Midstream specimens of urine from patients having UTI were detected by way of ordinary culture and sensitive test of medicine by K-B method. In 706 tested samples, 476 pathogenic bacteria were segregated. The positive rate of The pathogens consisted mainly of Escherichia, Enterococcus, staphylococcus, Klebsiella, Proteusspecies. The results of susceptibility test showed: For 465 strains of pathogenic bacteria except 11 strains of epiphyte, the largest percentage of drug resistance was as follow: Penicillin 76%, Ampicillin 70%; The smallest percentage of drug resistance was as follow: Imipenem 2%, Vancomycin 0%. [Conclusion] Drug resistance monitoring of diarrheogenic pathogenic bacteria has important significance in clinical drug treatment.