经动脉新辅助化疗治疗巨块型宫颈癌疗效分析

Efficency of intra-artery neoadjuvant chemotherapy for cervical cancer

目的评价经动脉新辅助化疗(Neoadjuvantintra-arterialchemotherapy,NAIC)治疗宫颈癌的疗效。方法随机抽取随访成功的35例采用NAIC方法治疗的宫颈癌病人,与单纯手术的病人在术后病理及生存率等方面进行分析对比。结果经NAIC治疗的病人手术时肿瘤的平均缩小率为82.9%,所有病人手术切缘均未见癌细胞。术后5年生存率为77.14%而单纯手术的病人的5年生存率为51.43%,二者对比具有统计学意义(P<0.05)。结论经动脉新辅助化疗配合妇科手术治疗宫颈癌可以降低手术难度,提高病人生存率。

To evoluate the efficacy of neoadjuvant intra-arterial chemotherapy for cervical cancer. Thirty-five patients who had been treated by NAIC before surgery and also be well followed was randomize selected to compare with the patients who had been treated only by operation, their pathyology and survival rate were studied. The patients who had been treated by NAIC have a average shrinkage of tumor about 82.9%, and there are no cancer cell remained after operation. The 5-year survival rate of the two group was 77.14% and 51.43%. There were statistic significance of the two (P<0.05). [Conclusion] NAIC can make the surgical easier and improve the survival rate of the patient suffering from cervical cancer.