可手术非小细胞肺癌淋巴结转移情况的分析

Clinical analysis of lymphatic metastases for operable non-small cell lung cancer (NSCLC)

目的探讨可手术的非小细胞肺癌(NSCLC)淋巴转移的特点及其与淋巴结最大直径的关系。方法回顾性分析行肺叶切除加系统性纵隔淋巴结清扫术的可切除的NSCLC淋巴结的病理特点。结果可手术的NSCLC56例,淋巴结转移36例,占64.3%,纵隔(N2)和肺内(N1)淋巴结转移均超过50.0%。N2站淋巴结按其最大直径≤1.0cm,>1.0cm且≤2.0cm,>2.0cm分为三个等级,其转移率分为24.0%,46.0%和80.0%,两者间的相关分析:χ2=28.751,ν=2,P<0.001,rP=0.31;同样地,N1站淋巴结的转移率分别为32.6%,44.9%和64.7%,两者间的相关分析:χ2=7.014,ν=2,0.025<P<0.05,rP=0.20。结论可手术的NSCLC淋巴结转移相当的常见,淋巴结转移随其最大直径的增加相应增加,两者间呈正相关关系。

To explore the characteristics of lymphatic metastases and the relationship between lymphatic metastases and it's most diameter for operable non-small cell lung cancer (NSCLC). Retrospective analysis was performed to the pathological characteristics in operable NSCLC undergone with classical lobectomy and radical systematic mediastinal lymphadenectomy. There were 56 cases surveyed, 36 patients existed lymphatic metastases, the rate was 64.3%. The rates of lymphatic metastases,both mediastinal(N2) and inner pneumonic (N1), were more than 50%. Reference to their most diameter, the N2 lymph nodes were divided into three groups: not more than 1.0 cm, between 1.0 cm and 2.0 cm, more than 2.0 cm. Respectively, the rate of lymphatic metastases was 24.0%, 46.0%, 80.0%. The correlation analysis result between lymphatic metastases and their most diameter was: χ2=28.751,ν=2,P <0.001, rP =0.31. Similarly, the rate of N1 lymph nodes was 32.6%, 44.9%, 64.7% respectively. The correlation analysis result was: χ2=7.014,ν=2,0.025<P <0.05, rP =0.20. [Conclusion] The lymphatic metastases of operable NSCLC is rather popular. The rate of lymphatic metastases increases followed by their most diameter, positive correlation exists between them.