过量酒精致睾丸损伤后的自然修复及其与生精周期的关系

The natural recovery of testis suffering from drinking from drinking alcohol excessively and the cycles of spermiogenesis.

目的 探讨大鼠睾丸在过量酒精损伤后的自然恢复及其与生精周期的关系。方法 用白酒灌胃制备睾丸毒性损伤模型。停止灌酒 1～ 2个生精周期后检测睾丸的组织学、精子质量及血清性激素的含量。结果 酒精使大鼠睾丸有明显的形态学改变 ,精子质量降低 (P <0 .0 1) ,性激素水平下降。经过 2个生精周期的恢复各项指标有了明显的改善 (P >0 .0 5 )。结论 酒精对睾丸的损伤是可逆性的 ,但恢复的时间比损伤时所用时间要长。

Objective: Study the natural recover of testicle suffering from drinking alcohol excessively and the cycles of spermiogenesis it took. Metheds: Making the sexual organs injured models of rats by alcohol. After stopping alcohol one or two cycles of spermatogenic process, test the sex hormone,sperm quality, testicle histology. Results: Drinking alcohol excessively can cause the sexual organs injury(P<0.01). After stopping drinking alcohol two cycles of spermatogenic process,each item just recovery to normal's. Conclusion: Alcohol is harmful for sexual system and it can naturaly turn to normal and it takes at least two cycles of spermiogenesis.