万托林联合普米克治疗小儿哮喘急性发作疗效观察

Efficacy of combined ventolin and pulmicort inhalation in treatment of acute onset of children asthma

目的 观察万托林联合普米克治疗小儿哮喘急性发作的疗效。方法 将哮喘患儿随机分为 2组 ,对照组 2 6例予以常规治疗 ;治疗组 2 6例 ,在常规治疗基础上加用万托林和普米克 ,观察治疗前后 1s用力呼气量 (FEV1) ,用力肺活量 (FVC) ,肺活量 (VC) ,最大呼气流量 (PEFR)。对结果采用配对t检验。结果 治疗组治疗前后病情明显改善 ,治疗前后比较FEV1,分别为 (0 77± 0 4 1)L和 (1 18±0 2 5 )L ,P <0 0 5 ;FVC分别为 (1 2 3± 0 2 7)L和 (1 75± 0 37)L ,P <0 0 5 ,VC分别为 (1 5 1± 0 2 2 )L和 (2 38± 0 36 )L ,P <0 0 5 ;PEFR分别为 (2 2 3± 0 73)L/s和 (2 76± 0 75 )L/s ,P <0 0 5。对照组治疗前后肺功能改善不明显 ,P >0 0 5。两组总有效率分别为 92 3%和 76 % ,治疗组明显优于对照组 (χ2=6 38,P <0 0 1)。

Objective To observe efficacy of combined ventolin and pulmicort in treatment of acute onset of children asthma.Methods Children with asthma were randomly divided into two groups;twenty-six cases of control group were treated with common therapy,twenty-six cases of study group were treated with combined ventolin and pulmicort inhalation in addition of FEV 1,FVC,VC,PEFR were investigated after treatment.Results The children in study group were much more improved,comparing with those in control group.FEV_1 were (0.77±0.41)L(P<0.05),FVC were (1.23±0.27)L and (1.25±0.37)L(P<0.05),VC were (1.51±0.22)L and (2.38±0.36)L (P<0.05),PEFR were (2.23±0.73)L/s and (2.76±0.75)L/s (P<0.05) respectively.The lung function of control group were not improved before and after treatment (P>0.05).Two groups efficiency were 92.3% and 76% respectively.The study group is significantly better than those in control group.Conclusion Combined ventolin and pulmicort inhalation in treatment of acute onset of children asthma are effective.