关于细胞毒因子抗肿瘤活性的研究

STUDY ON THE ANTI TUMOR ACTIVITY OF CYTOTOXIC FACTOR

用抗肿瘤免疫RNA诱生家兔,用体外细胞毒实验证明.i—RNA致敏血清对人和鼠的肿瘤细胞株有不同程度的杀伤作用,从血清中的细胞毒活性粗提液经局部和静脉注入实体瘤鼠体内,见肿瘤组织有出血、坏死、细胞核溶解,消失等现象。

Rabbits were sensitized by i-RNA then the serum of the rabbits was collected and tested for the cytotoxic activity. The partly separated and purited immuned serum was injected into the Ehrlich 180 solid tumors of BALB/c mice. The fascinating hemorhagic necrosis were find in the solid tumor