夏连颗粒(甲康)治疗亚急性甲状腺炎的临床研究

Clinical Study on the treatment of subacute thyroiditis with

目的探讨纯中药制剂夏连颗粒(甲康)对亚急性甲状腺炎的临床疗效及停药后的复发率。方法对102例亚急性甲状腺炎随机分为三组;甲康治疗组(A 组),对照组分别为消炎痛、泼尼松(B 组)及甲康、消炎痛合用泼尼松(C组),观察其疗效、疗程及停药后的复发率。结果疗效;三组均全部治愈,无显著差异。疗程;A 组:4～6周(χ±SD:27.89±13.56天),B 组:4～6周(X±SD:31.71±14.32天),C 组:2～4周(18.79±9.72天)。A 组与 B 组比较无显著差异(P>0.05),但 C 组与 A、B 组比较有显著差异(P<0.05)。复发率:A 组3.22%(1/31),B 组21.21％(7/31),C 组2.63%(1/38)。A 组与 B 组比较有显著差异(P<0.05),A 组与 C 组比较无显著差异(P>0.05)。结论纯中药制剂夏连颗粒(甲康)对亚急性甲状腺炎治疗有效,特别是中西医药联合用药,疗效更佳,起效快、疗程短、复发率低。此项研究结果表明,夏连颗粒(甲康)可以应用于临床。

Objective To explore the clinical effect and the recurrent rate of Subacute thyroiditis with the pure Chinese traditional prepara- tion XiaLian granules(Jia Kang).Methods 102 subacute thyroiditis cases were randomly divided into three groups.Group A:Jia Kang treat- ment(treatment group).Group B:cases treated by Antifan and Delta cortisone.Group C:Jia Kang,Antifan and Delta cortisone(control group).The therapeutic effect,the total course of treatment and the recurrent rate were observed.Results the therapeutic effect:All the cases were cured in three groups.The results Showed no significant differences.The total course of treatment:Group A:4～6 weeks(x±SD:27.89 ±13.56days),Group B:4～6 weeks(x±SD:31.71±14.32 days),Group C:2～4 weeks(x±SD:18.79±9.72 days).There were no significant differences in Group A and Group B(P>0.05).The difference between Group C and Group B,A was significant P<0.05). The recurrence rate:Group A:3.22%(1/31),Group B:21.21%(7/31),Group C:2.63%(1/38).There were significant differ- ences in Group A and Grape B(P<0.05),but there were no differences in Group A and Group C(P>0.05).Conclution The treatment of subacute thyroiditis with the pure Chinese traditional preparation——XiaLian granules(Jia Kang)is effective.Better action,higher efficacy, shorter therapeutic course and lower recurrence are the benefit of integrated traditional Chinese and western medicine treatment for subcute thy- roiditis especially.The results obtained in this study:Xialian granules(Jia kang)can be used in clinical.