1Zauber NP. Sabbath Solitare M, Marotta SP, et al. K-ras mutation and loss of heterozygosity of the adennnmtous pnlyposis coli gene in patients with eolorectal adenomas with in situ carcinoma. Cancer,1999.86(1) :31-36.
2Zauber NP,Sabbath Solitare M, Marotta SP,et al. Molecular changes in she Ki-ras and APC genes in colorectal adenomas and carcinomas arising in she same patient. J Pathol,2001,193(3):303-309.
3Blaker H, Graf M, Rieker R J, et al. Comparison of losses of heterozygosity and replication errors in primary colorectal carcinomas and corresponding liver metastases. J Pathol, 1999,188(3) :258-262.
4Zauber P. Sabbath Solitare M, Marotta SP, et al. Molecular changes in the Ki-ras and APC genes in primary colorectal carcinoma and synchronous metastases compared with the findings in accompanying adenomas. Mol Pathol,2003,56(3) :137- 140.
5Umetani N .Sasaki S,Watanabe T,et al. Genetie alterations in ulcerative colitis-associated neoplasia focusing on APC K-ras gene and microsatellite instability. Jpn J Cancer Res. 1999,90(10): 1081-1087.
6Kanazawa T, Watanabe T, Kazama S,et al. Poorly differentiated adenocarcinoma and mucinous carcinoma of the colon and rectum show higher rates of loss of heterozygosity and loss of E-cadherin expression due to methylation of promoter region. Int J Cancer. 2002,102(3) :225-229.
7Choi SW, Lee KJ, Bae YA, et al. Genetic classification of colorectal cancer based on chromosomal loss and mierosalellite instability preditets survival. Clin Cancer Res, 2002,8 ( 7 ) : 2311 - 2322.
8Zhang H, Arhnlan G, Sun XF. Codon 201 polynlorphism of DCC gene is a prognostic factor in patients wilh coloreetal cancer. Cancer Detect Prey ,2003,27(3 ) :216-221.
9Gareia JM, Rodriguez R, Dominguez G, el al. Prognostic significance of the allelie loss of the BRACI gene in eoloreetal cancer. Gut,2003,52(12) :1756- 1763.
10Iniesta P, Massa M J, Gonzalez Quevedo R, et al. Loss of helerozygosity at 3p23 is correlated with poor survival in patients with eoloreetal carcinoma. Cancer, 2000,89 ( 6 ) : 1220- 1227.
