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VEGFR-3在肿瘤淋巴管转移中的作用 被引量:6

Vascular endothelial growth factor C promotes lymphangiogenesis in tumour metastasis
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摘要 VEGFR 3主要在成熟组织的淋巴管内皮细胞上表达,肿瘤分泌的VEGF C、VEGF D与 之结合后可诱导淋巴管内皮细胞增殖和迁移,刺激淋巴管的新生,介导肿瘤淋巴道的转移。通过竞 争性抑制VEGFR 3的信号转导可有效阻止肿瘤淋巴管的转移,最终达到提高治疗肿瘤的作用。
作者 张洁 周彩存
出处 《国外医学(肿瘤学分册)》 2005年第2期113-115,共3页 Foreign Medical Sciences (Cancer Section)
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参考文献23

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同被引文献37

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