直肠粘膜吸引活检诊断先天性巨结肠

DIAGNOSIS OF IIIRSCHSPRUNG' S DISEASE WITH RECTAL SUCTION BIOPSY

采用直肠粘膜吸引活检技术诊断可疑先天性巨结肠26例。除2例取材不满意外,5例找到粘膜下神经节细胞,排除先天性巨结肠;19例未找到粘膜下神经节细胞,诊断先天性巨结肠,其中12例经根治术后病理切片进一步证实。认为采用本法诊断巨结肠,具有准确安全,方法简便等优点。作者对本法的操作要点及粘膜下神经节细胞辨别方法作了探讨。

26 cases with suspected Hischsprung' s disease (HD) were diagnosed using rectal suction biopsy. Except for 2 cases of unsatisfactory biopsy, HD was excluded in 5 cases in which submucous ganglion cell was found microscopically. 19 cases were diagnosed as HD without submucous ganglion cell being found, 12 of which were further confirmed patholoigically after radical treatment. Meanwhile, the manipulating mainpoints of the biopsy and the pathological identification of the submucous ganglion cell were discussed. It was held that the method to diagnose HD had the advantages of being correct, safe, simple and convenient.