四烷基氮杂对环仿的合成

The Synthesis of Tetraalkylazaparacyclophane

报道N,N’—二对甲苯磺酰基—4,4’一二氨基二苯甲烷和1,6一二溴己烷在高度稀释的条件下环化得到1,8,22,29一四氮杂[8.1.8.1]对环仿,接着与溴代烷作用得到3种未曾报道的1,8,22,29一四烷基一1,8,22,29一四氮杂[8.1.8.1]对环仿。

N, N'-Ditosy1-4, 4'-diaminodiphenyl methane and 1,6-dibromo-hexane are cyclized under high-dilution conditions to give 1, 8, 22, 29-tetraazal[8.1.8.1]paracyclophane. from which three new 1, 8, 22, 29-tetraalkyl-1, 8, 22, 29-tetraaza [8.1.8.1]paracyclophanesare synthesized.