6Bombard EM,Schmidt U,Loser E.Time course of enzyme induction in liver and kidneys and absorption,distribution and elimination of 1,4-dichlorobenzene in rats[J].Toxicology,1998,131:73-91.
7Hawkins DR,Chasseaud LF,Woodhouse RN,et al.The distribution excretion and biotransformation of p-dichlorobenzene in rats after repeated inhalation,oral and subcutaneous dose[J].Xenobiotica,1980,10:81-95.
8Yoshida T,Andoh K,Kosaka H,et al.Inhalation toxicokinetics of p-dichlorobenzene and daily absorption and internal accumulation in chronic low-level exposure to humans[J].Arch Toxicol,2002,76:306-315.
9Hill RH Jr,Ashley DL,Head SL,et al.p-Dichlorobenzene exposure among 1,000 adults in the United States[J].Arch Environ Health,1995,50:277-280.
10EPA.Broad scale analysis of the FY82 National Human Adipose Tissue Survey Specimens.VolⅡ.Volatile organic Compounds[R].EPA 560/5-86-036.Washington DC,1986.
2Tegethoff K,Herbold BA,Bomhard EM.Investigations on the mutagenicity of 1, 4-dichlorobenzene and its mainmetabolite 2, 5-dichlorophenol in vivo and in vitro[].Mutation Research.2000
3Sasaki YF,Izumiyama F,Nishidate E,et al.Detection of rodent liver carcinogen genotoxicity by the alkaline single-cell gel electrophoresis(Comet)assay in multiple mouse organs(liver, lung, spleen, kidney, and bone marrow)[].Mutation Research.1997
4Oikawa S,Kawanishi S.Copper-mediated DNA damage by metabolites of p-dichlorobenzene[].Carcinogenesis.1996
5Carbonell E,Puig M,Xamena N,et al.Sister-chromatid exchanges(SCE)induced by p-dichlorobenzene in culturewd human lymphocytes[].Mutation Research.1991
6Morita T,Asano N,Awogi T,et al.Evaluation of the rodent micronucleus assay to screen IARC carcinogens(group1, 2a, and 2b), the summary report of the 6th collaborative study by CSGMT/JEMS.MMS[].Mutation Research.1997
7Canonero R,Compart GB,Mottioli F,et al.Testing of p-dichlorobenzene and hexachlorobenzene for their ability to induce DNA damage and micronucleus formation in primary cultures of rat and human hepatocytes[].Mutagenesis.1997
3Barter JA, Sherman JH. An evaluation of the carcinogenic hazard of 1,4-dichlorobenzene based on internationally recognized criteria [J]. Regnl Toxicol Pharmacol, 1999,29( 1 ) :64 -79.
4Hissink AM, Oudshoorn M J, Van Ommen B, et al. Species and strain differences in the hepatic cytochrome P450-mediated biotransformation of 1,4-dichlorobenzene [J]. Toxicol Appl Pharmacol, 1997,145( 1 ) :1 -9.
5Younis HS, Parrish AR, Glenn Sipes I. The role of hepatocellular oxidative stress in Kupffer cell activation during 1, 2-dichlorobenzene-induced hepatotoxicity [J]. Toxicol Sci ,2003,76( 1 ) :201 - 211.
6Hawkins DR, Chasseaud LF, Woodhouse RN, et al. The distribution excretion and biotransformation of p-dichloro benzene in rats after repeated inhalation, oral nd subcutaneous doses [J]. Xenobiotica, 1980,10 (2) : 81 - 95.
7Mizutani T, Nakahori Y, Yamamoto K. p-Dichloro-benzene-induced hepatotoxicity in mice depleted of glutathione by treatment with buthionine sulfoximine [J]. Toxicology, 1994,94 (1/3) : 57 - 67.
8Aiso S, Arito H, Nishizawa T, et al. Thirteen-week inhalation toxicity of p-dichlorobenzene in mice and rats [J]. J Occup Health,2005,47 (3) :249 - 260.
9Lake BG, Cunninghame ME, Price RJ. Comparison of the hepatic and renal effects of 1,4-dichlorobenzene in the rat and mouse[J]. Fundam Appl Toxicol, 1997,39 ( 1 ) :67 -75.
10Hassink AM, Dunnewijk R,van Ommen B,et al. Kinetics and metabolism of 1,4-dichlombenzene in male wister rats:no evidence for quinone metabolites[J]. Chem Biol Interact, 1997,103 (1) : 17 - 33.
