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肿瘤坏死因子相关凋亡诱导配体及其诱导肿瘤细胞凋亡机制的研究进展 被引量:4

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摘要 肿瘤坏死因子相关凋亡诱导配体 (TRAIL)与死亡受体结合后 ,可启动凋亡信号的转导。它对肿瘤细胞的高效杀伤作用使其成为最具有潜力的肿瘤治疗药物 ,但在TRAIL的研究领域中仍然存在许多热点问题有待解决。本文综述了近年来TRAIL诱导肿瘤细胞凋亡的胞内机制、抗肿瘤活性及安全性问题的研究进展。
作者 方芳 王爱平
出处 《国外医学(药学分册)》 2005年第1期6-10,共5页 Foreign Medical Sciences(Section of Pharmarcy)
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