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EFFECTS OF ISATIN ON ROTATIONAL BEHAVIOR AND DA LEVELS IN CAUDATE PUTAMEN IN PARKINSONIAN RATS

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摘要 Isatin was a potent endogenous monoamine oxidase (MAO) inhibitor that is more active against MAO-B than MAO-A. The acute effects of isatin on apomorphine (APO)-induced rotations were evaluated in Parkinsonian rats induced by 6-hydroxydopamine (6-OHDA) lesion. Furthermore, the effects of isatin on DA release in caudate putamen (CPu) of model and normal rats were monitored using fast cyclic vohammetry (FCV).
出处 《青岛大学医学院学报》 CAS 2002年第2期132-132,共1页 Acta Academiae Medicinae Qingdao Universitatis
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