高血压病左室舒张功能组织多普勒改变与临床分级对比分析

Contrast Analysis between Left Ventricular Diastolic Function by Doppler Tissue Imaging and Clinical Classification in Hypertention

目的:初步探讨高血压病患者左室舒张功能改变与临床分级的关系。方法:参考世界卫生组织/国际高血压 协会(WHO/ISH)对高血压病诊断分级标准,选择临床确诊的高血压病1级20例,2级20例,3级组18例,采用脉 冲组织多普勒测定二尖瓣环侧壁段朝向心房侧的负向舒张早期波(e峰)、舒张晚期波(a峰),并计算e/a比值。结 果:各组间e峰及a峰无显著性差异,e/a比值:1级组(0.81±0.22),2级组(0.68±0.16),3级组(0.62±0.11),1 级组与2级组、3级组比较有统计学差异,而2级组与3级组之间无统计学差异。结论:组织多普勒e/a值在一定 程度上可反映不同级别高血压患者的左室舒张功能改变。

Objective: To examine the relationship between left ventricle diastolic function and clinical classification in hypertention.Methods:Echocardiography of 58 cases with hypertention confirmed clinically was analyzed, which included 20 cases of grade 1,20 grade 2,18 grade 3. The peak early diastolic(“e”wave),peak late diastolic(“a”wave) velocities and the e/a ratios at lateral mitral valve anulus were measured by pulsed wave tissue imaging.Results:The velocity of “e” peak and “a” peak at mistral valve annulus were no different between the groups;e/a ratios in grade 1 was 0.81±0.22,grade 2 was 0.68±0.16,and grade 3 was 0.62±0.11. There was much different between grade 1 and grade 2 or grade 3,but no different between grade 2 and grade 3.Conclusion:The e/a ratios can possibly reflect diastolic dysfunction of left ventricular in the different grade hypertension.