摘要
目的 探讨血清α1 酸性糖蛋白 (α1 AG)的水平变化在糖尿病继发感染中的临床应用价值。方法 用免疫比浊法对 30例糖尿病继发感染患者、25例糖尿病无感染患者、20例正常人的血清α1 AG进行检测,并与反映感染的敏感指标C反应蛋白 (CRP)相比较。结果 继发感染组α1 AG水平明显高于无感染组及正常对照组 (P均 <0. 001 ),无感染组略高于正常对照组,但无显著性差异 (P>0. 05 )。α1 AG与CRP水平显著正相关 (r=0. 912,P<0. 01 )。继发感染组感染控制前后血清α1 AG水平有显著差异 (P<0 001 )。结论 血清α1 AG水平与有无感染密切相关,动态观察血清α1 AG水平有助于糖尿病继发感染的早期诊断及抗感染疗效的观察。
Objective To investigate the clinical application of serum α 1-acid glycoprotein (α 1-AG) to diabetes mellitus (DM) with secondary infection.Methods The serum α 1-AG levels of 30 DM patients with secondary infection and of 25 DM patients without infection were measured by immunoturbidimetry, and then were investigated whether correlativity with the level of serum c-reactive protein (CRP) existed.Results The α 1-AG level of DM patients with infection was obviously higher than that of the patients without infection and that of normal controls (P<0.001). The α 1-AG level of DM patients without infection was higher than that of normal control, but the difference was not significant (P>0.05). Positive correlation was shown between serum α 1-AG and CRP (r=0.912, P<0.01). Significant difference in α 1-AG level in DM patients was found between pre-and post-treatment (P<0.001).Conclusion The α 1-AG level is significantly correlated with DM patients with infection. Its detection is helpful to the early diagnosis of DM with infection and to the assessment of therapeutic effect.
出处
《临床军医杂志》
CAS
2005年第1期11-12,共2页
Clinical Journal of Medical Officers
关键词
Α1-酸性糖蛋白
糖尿病
感染
α 1-acid glycoprotein
diabetes mellitus
infection