踝臂血压比值与脑梗死的关系

ANKLE-BRACHIAL-PRESSURE INDEX IN PATIENTS WITH CEREBRAL INFARCTION

目的 探讨踝臂血压比值与脑梗死的关系。方法 研究对象为 2 0 0例脑梗死病例和 2 0 0例非脑梗死病例组成 ,二组年龄和性别相匹配 ,二组均采用袖带式自动血压计进行测量血压 ,分别测量左踝和左上臂的血压 3次 ,取其收缩压的平均值作为踝臂血压比值。结果 脑梗死组年龄 (63 .6± 1 2 .5)岁 ,对照组年龄 (64 .1± 1 3 .2 )岁 ,二组年龄之间差异无统计学意义。脑梗死组的踝臂血压比值为0 .92± 0 .0 7;对照组为 1 .1 0± 0 .0 6 ,二组踝臂血压比值差异有统计学意义。脑梗死组的踝臂血压比值 <0 .90的占 51 % ;而对照组的踝臂血压比值 <0 .90的占 4 % ,二组之间差异有统计学意义。结论 颈动脉狭窄和低的踝臂血压比值均被认为是全身动脉硬化疾病的标志 ,踝臂血压比值很容易测量 ,建议对存在脑动脉硬化的老年人如果踝臂血压比值 <0 .90应高度警惕脑梗死的发生 ,并应积极进行干预 。

Objective To investigate the effect of the ankle-brachial-pressure index (ABPI) - the radio of the ankle on the brachial systolic blood pressure - on indication of occlusive atherosclerotic disease in the brain. Methods Study population consisted of 100 patients with ischaemic stroke and gender-matched. Systolic blood pressure was measured three times in the left arm and at the left ankle with an automated recorder,while the subject was lying down. The cuff was removed and replaced between measurements. The mean of these measurements was used to calculate the ABPI. Results The mean ± SD age of cerebral infarction group was (63.6±12.5) years. and the mean ± SD age of contral group was(64.1±13.2) years.There was not significant difference between the ages of two groups However,The mean ± SD ABPI of cerebral infarction group was 0.92±0.07, and the mean ± SD ABPI of contral was 1.10±0.06 . There was a significant difference between the ABPI of two groups (P<0.01).In addition, ABPI less than 0.90 was 51% in cerebral infarction group,and 4% in contral group. There was also a significant difference between the two groups by x2 test (P<0.01). Conclusion Cerebral infarction is typically characterized by occlusion of one or more cerebral arteries secondary to atherosclerosis. Since carotid stenosis and a low ABPI can both be regarded as markers of generalized arteriosclerotic disease,one might have expected a similar prognosis in the cerebral infarction.Our results showed that ABPI is much less in cerebral infarction than in control,and indicated that a low ABPI can be regarded as a useful marker of cerebral infarction. Since ABPI measurement is very easy to manipulating,it can be clinically used to monitor progression of severity of obstruction in cerebral arteries.