电针治疗对男性免疫性不育症一氧化氮及微量元素的影响

Effects of electroacupuncture on nitric oxide and trace elements in patient of male immune infertility

目的 :探讨针刺治疗男性免疫性不育症的机理。方法 :将 4 0例男性不育症抗精子抗体阳性的患者 ,按就诊顺序分为 2 0例俞原配穴针刺组和 2 0例口服强的松西药组 ,经治疗 2个疗程后 ,观察其治疗前后的一氧化氮 (NO)及微量元素的变化情况。结果 :电针组的血清NO含量有显著的下降 ,头发的锌、铜、铁等微量元素含量均有不同程度的提高 ,其效果明显优于西药对照组 (P <0 0 5 )。结论 :俞原配穴电针法治疗男性免疫性不育症的机理 ,可能与调节不育症患者的一氧化氮及微量元素的含量有关。

Objective To study on mechanisms of acupuncture in treatment of male immune infertility. Methods Forty cases of male immune infertility with positive anti-sperm antibody were divided into combined shu-point and source-point needling group (electroacupuncture group, n=20) and oral prednisone group (control group, n=20). They were treated for 2 therapeutic courses. Changes of nitric oxide (NO) and trace elements before and after treatment were investigated. Results Serum NO content in the electroacupuncture group decreased significantly, and Zn, Cu and Fe contents in the hair increased in varying degrees, superior to the control group (P<0.05). Conclusion The mechanism of the combined shu-point and source-point electroacupuncture in treatment of male immune infertility is possibly related with regulation of the contents of NO and trace elements in the patient.