四物消风洗剂临床用量的安全性评价

Evaluation of the reliability of Siwuxiaofeng Lotion

目的 通过临床前毒理学试验———急性皮肤毒性试验 (限量试验 )和过敏试验 (限量试验 )考察四物消风洗剂临床用量的安全性。方法 ①对健康家兔进行皮肤急性毒性试验 ;②对健康豚鼠进行皮肤过敏性试验。结果 四物消风洗剂对家兔皮肤未引起急性毒性反应和刺激反应。对豚鼠完整皮肤无致敏作用。结论 四物消风洗剂用于临床安全。

Objective To examine the reliability of Siwuxiaofeng Lotion by the clinic toxicological experiments.Methods ①Acute dermal toxicity test were conducted in healthy rabbits.②Acute dermal sensitivity test was performed in guinea pigs.Results Siwuxiaofeng Lotion had no acute toxicity or irritation to the skin of rabbits,and was not allergy-inducing to the skin of guinea pigs.Conclusion Siwuxiaofeng Lotion is safe and nontoxic and can be used in clinical practice.