庆大霉素致老年人急性肾衰两例报告

Report on Two Cases of Old People Suffering Acute Renal Failure after the Treatment with Gentamicin

庆大霉素对肾脏的毒性作用已引起临床医师的重视,作者碰到两例老年患者用药剂量不大且时间短却导致严重后果,现报告如下: 临床资料 例一:蔡×,女性,75岁,1988年9月1日突然昏迷急诊入院,患者入院前4天因吃不新鲜食物而发生急性腹泻并呕吐、在家中静滴庆大霉素每天16万单位,共3天,第4天清早发现昏迷不醒而急诊入院,入院时神志不清,呼吸28次深而大,小便蛋白廾。

This article reports the Clinicxal process of how even a small amount ofgentamicin could result in acute renal failure in two old peoples and expounds the toxic effect of gentamicin on the kidneys. It shows that care must be taken in treating old people with gentamicin especially those who have signs of dehydration or renal insufficiency.