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Cu,Zn SOD in Shandong families with amyotrophic lateral sclerosis

Cu,Zn SOD in Shandong families with amyotrophic lateral sclerosis
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摘要 Objective: To understand the relationship between Cu,Zn SOD and amyotrophic lateral sclerosis. Methods: The patients were clinically examined and classified according to the E1 Escorial Criteria, then we obtained blood samples from the patients for Cu,Zn SOD analysis and SOD assay. Amino acid analysis of Cu,Zn SOD were fully automated in instruments called amino acid analyzers. SOD assay was determined by cytochrome c method Results: Amino acid analysis of Cu,Zn SOD from patients with familial ALS was normal. The activity of Cu,Zn SOD was normal both in familial and sporadic form of ALS compared with normal person. Conclusion: Amyotrophic lateral sclerosis is not related to Cu,Zn SOD. Objective: To understand the relationship between Cu,Zn SOD and amyotrophic lateral sclerosis. Methods: The patients were clinically examined and classified according to the E1 Escorial Criteria, then we obtained blood samples from the patients for Cu,Zn SOD analysis and SOD assay. Amino acid analysis of Cu,Zn SOD were fully automated in instruments called amino acid analyzers. SOD assay was determined by cytochrome c method Results: Amino acid analysis of Cu,Zn SOD from patients with familial ALS was normal. The activity of Cu,Zn SOD was normal both in familial and sporadic form of ALS compared with normal person. Conclusion: Amyotrophic lateral sclerosis is not related to Cu,Zn SOD.
机构地区 Dept.ofBiochemistry
出处 《泰山医学院学报》 CAS 2004年第4期339-340,共2页 Journal of Taishan Medical College
关键词 Cu Zn SOD SPORADIC amyotrophic LATERAL SCLEROSIS FAMILIAL amyotrophic LATERAL SCLEROSIS Enzyme activi-ty Cu,Zn SOD Sporadic amyotrophic lateral sclerosis Familial amyotrophic lateral sclerosis Enzyme activity
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