巴洛沙星的合成路线

Graphical synthetic routes of balofloxacin

目的:合成巴洛沙星。方法:对其合成路线进行了分类和比较。结果与结论:路线1②和2②适于工业化生产。

A comparison of various synthetic methods of balofloxacin,a new quinolone type ofantibacterial agent,was made,suggesting that both routes 1② and 2② are favorable to the manufactur-ing.