妊娠相关性血浆蛋白-A与急性冠状动脉综合征

Pregnancy Associated Plasma Protein-A and Acute Coronary Syndrome

近来发现妊娠相关性血浆蛋白 -A(PAPP -A)与急性冠状动脉综合征 (ACS)有关。在ACS患者血清中 ,其浓度明显增高 ,预示可以作为不稳定型心绞痛和急性心肌梗死新的标记物。本文就PAPP -A的生物学特点、作用机制及在急性冠脉综合征中的临床意义做一简要综述。

Pregnancy associated plasma protein-A(PAPP-A)has recently been shown to be associated with acute coronary syndromes(ACS). In the patient of acute coronary syndrome, The concentration of PAPP-A rise significantly which indicate that it can be used as an additional marker for ACS. In the patient of acute coronary syndrome, The concentration of PAPP-A rise significantly which indicate that it can be used as an additional marker for ACS. This review introduces the molecular structure and biological character of PAPP-A and its clinical meaning in ACS.