无痛人工流产术加米索前列醇终止早孕

Clinical Study on Termination of Early Pregnancy with Painless Artificial Aborti on Plus Misoprostol Clinical Study of Misoprostol's Assistant Effect with Painless Artificial Abortion on Termination of Early Pregnancy

目的:探讨无痛人工流产前、后舌下含化米索前列醇终止早孕的临床效果。方法:将孕8～10周需终止妊娠并要求无痛人工流产的97例孕妇随机分为观察组(49例)和对照组(48例)。前者在用丙泊酚及芬太尼行无痛人工流产前半小时及其后分别舌下含化米索前列醇0 .4mg ;后者不用米索前列醇。观察两组术中宫颈松弛扩张情况、宫缩幅度、术中出血量及术后阴道流血时间。结果:两组宫颈松弛扩张情况无差异;观察组宫缩幅度明显大于对照组(P <0 .0 5 ) ;且易于手术操作,术中出血量、术后阴道流血时间均明显的小于或短于对照组(P分别为<0 .0 1和<0 .0 5 )。结论:无痛人工流产前、后舌下含化米索前列醇可增强子宫收缩、手术易于操作、术中出血少、术后阴道流血时间短,值得临床推广应用。

Objective:To study the clinical effect on termination of early pregnancy by giving misoprostol sublingually before and after painless artifici al abortion.Methods:97 women at the gestational age of 8-10 w eeks who needed termination of pregnancy and asked for painless artificial abor tion were divided randomly into test group (49 cases) and control group (48 case s) . The test group were given 0.4 mg of misoprostol sublingually half an hour b efore and after th e painless artificial abortion with propofol and fentanyl as anaesthetic and ant algic . The control group had the same treatment as the test group but without misoprostol. Laxation and dilatation of the cervix during operation, r ange of uterine contraction, amount of bleeding during operation and postopera tive colporrhagia time were observed. Results:There was no diffe rence in l axation and dilatation of the cervix between the two groups. Range of uterine c ontraction in test group was markedly larger than that in control group (P <0.05), in favor of operating. In test group, the amount of bleeding durin g operation is significantly smaller(P<0.01), and the postoperative colporr hagia time was notablely shorter than that in control group (P<0.05 ) . Conclusions:Misoprostol given before and after painless arti ficial abortion may inten sify uterine contraction and make operating easier. It helps to decrease th e amount of bleeding during operation and shorten the postoperative colporrhagia time. It is valuable to apply it clinically.[