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弥漫性掌跖角化病 被引量:5

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摘要 弥漫性掌跖角化病是一组临床表现多样、累及掌跖的皮肤病,表现为掌跖部皮肤弥漫性增厚,通常合并有其他外胚叶病变。由于这组疾病的临床表现重叠和多样性,很难进行分类。近年来,该病分子特征研究的进展有助于区分该病的不同型别,并提高了我们对皮肤生物学的认识。
出处 《国外医学(皮肤性病学分册)》 2005年第2期87-89,共3页 Foreign Medical Sciences(Section of Dermatology and Venereology)
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参考文献20

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同被引文献20

  • 1张宝荣,殷鑫浈,夏昆,丁美萍,胡正茂,郑敏,刘志蓉,夏家辉.一个表皮松解性掌跖角化病家系的KRT9基因突变分析[J].中华医学遗传学杂志,2004,21(6):570-573. 被引量:7
  • 2孙霞,殷鑫浈,邬玲仟,施小六,胡正茂,刘小平,潘乾,戴和平,夏昆,夏家辉.弥漫性掌跖角化病家系角蛋白9基因突变热点区的检测[J].中南大学学报(医学版),2005,30(5):521-524. 被引量:8
  • 3刘建军,郭淑兰.表皮松解性掌跖角化病1例[J].临床皮肤科杂志,2006,35(2):98-99. 被引量:1
  • 4殷鑫浈,张宝荣,丁美萍,张灏,夏昆,胡正茂.两个弥漫性掌跖角化病家系的病理特征与基因突变分析[J].遗传,2007,29(3):301-305. 被引量:7
  • 5Hatsell S J, Eady R A, Wennerstrand L, et al. Novel splice site mutation in keratin 1 underlies mild epidermolytic palmoplantar keratoderma in three kindreds[J]. J Invest Dermatol, 2001,116 (4):606-609.
  • 6Zhang X N, He X H, Lai Z, et al. An insertion-deletion mutation in keratin 9 in three Chinese families with epidermolytic palmoplantar keratoderma[J]. Br J Dermatol, 2005,152 (4) : 804- 806.
  • 7Yang M H, Lee J Y, Lin J H, et al. De novo mutation of keratin9 gene in two Taiwan Residents patients with epidermolytic palmoplantar keratoderma[J]. J Formos Med Assoc, 2003, 102 (7) :492-496.
  • 8Kimonis V, DiGiovanna J J, Yang J M, et al. A mutation in the V1 end domain of keratin 1 in non-epidermolytic palmarplantar keratoderma[J]. J Invest Dermatol, 1994,103 (6) : 764-769.
  • 9Kelsell D P, Stevens H P, Purkis P E, et al. Fine genetic mapping of diffuse non-epidermolytie palmoplantar keratoderma to chromosome 12q11-q13: exclusion of the mapped type Ⅱ keratins[J]. Exp Dermatol, 1999,8(5) : 388-392.
  • 10Hatsell S J, Eady R A, Wennerstrand L, et al. Novel splice site mutation in keratin 1 underlies mild epidermolytic palmoplantar keratoderma in three kindreds [J]. J Invest Dermatol,2001,116(4) :606-609.

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