前列腺癌首次治疗失败后的临床处理

Clinic Retreatment of Prostate Cancer after Initial Treatment Failure

本文总结了前列腺癌首次治疗失败后的临床处理经验。对85例临床资料齐全的病例分析、观察其恶化的临床表现、治疗方法及其疗效。结果16例病情稳定,占18.8％;69例出现局部复发或远处转移症状,占81.2％。主要恶化症状为骨痛、尿潴留、肾积水、血尿和脊髓压迫等、内分泌治疗和放疗仍是目前主要的治疗手段,内分泌治疗宜早不宜迟,间断性雄激素阻断治疗应予提倡,放疗对骨痛的缓解有一定价值。

To assess clinic retreatment experience of prostate cancer after initial treatment failure, We analysed and observed the clinic expressions, treatment methods and effects of deteriorative prostate cancer. The treatment includes bilateral orchidectomy, hormonotherapy, radiotherapy, TURP and suprapubic cys-tostomy. Of 85 prostate cancer patients, 16(18.8%) had favorable patient's condition, 69(81.2%) had the sign of local recurrence or distant metastasis. The main signs had the ostealgia, urine retention, hy-dronephrosis, hematuria and compresion of spinal cord. At present, the radiotherapy and hormonotherapy are still importent methods for deteriorative prostate cancer. The hormonotherapy must be early. The intermittent androgen suppression therapy can be advocated and radiotherapy is good effect for remission of ostealgia.