穴位注射灯芯灸联合干扰素治疗慢性乙型肝炎疗效观察

Observation on therapeutic effect of combined treatment of acupoint-injection,burning rush moxibustion and interferon on chronic hepatitis B

目的 :寻求提高干扰素 (IFN)治疗慢性乙型肝炎 (CHB)疗效的有效方法。方法 :95例CHB随机分为两组 ,均采用同剂量IFN肌注。疗程前 3个月治疗组同时另予胸腺肽注射液穴位注射、灯芯灸 ,对照组仅同时另予胸腺肽肌肉注射。观察比较两组患者肝功能、HBeAg、HBV DNA变化情况及整体应答率。结果 :治疗组疗效明显优于对照组 (P <0 0 1或P <0 0 2 5)。结论 :联合胸腺肽穴位注射。

Objective To search for an effective method to incr ease the therapeutic effeect of interferon (IFN) on chronic hepatitis B. Methods 95 cases of chronic hepatitis B were randomly divided i nto treatment group and control group who were treated by intramuscular injectio n of IFN. In the first 3 months of the course, the treatment group were added wit h acupoint-injection of thymosin injectio and burning rush moxibustion, and the control group were added with only intramuscular injection of thymosin. The hep atic function, HBeAg, HBV-DNA and the general response rate were compared betwe en the two groups. Results The therapeutic effect in the treatment group was bette r than that in the control group (P<0 01 or P<0 025). Conclusion Combination of acupoint-injection of thymosin with burning rush moxibustion can markedly increase the therapeutic effect of IFN on chronic hepatitis B.