针刺治疗慢性荨麻疹50例及其对血清补体C_3的影响

Effect of acupuncture on serum complement C_3 content in the patient of chronic urticaria

目的 :探讨有效提高慢性荨麻疹疗效的方法及其免疫机理。方法 :92例慢性荨麻疹患者随机分为观察组 50例和对照组 42例 ,观察组采用针刺合谷、血海、足三里、三阴交穴联合抗组胺药仙特敏治疗 ,对照组单纯使用仙特敏 ,观察疗效及治疗前后血清补体C3 的变化。结果 :观察组有效率92 0 % ,对照组有效率 73 6 % ,差异有显著性意义 (P <0 0 5) ;慢性荨麻疹患者血清补体C3 治疗前平均水平较健康成人低 ;观察组补体C3 水平治疗前后差异有显著性意义 (P <0 0 5)。结论 :针刺联合抗组胺药仙特敏疗效优于单纯仙特敏 ,且能相应提高患者的补体C3

Objective To probe into the method effectively incr easing therapeutic effect on chronic urticaria and its immune mechanism. Methods 92 cases of chronic urticaria were randomized to the a cupuncture group (n=50) treated by acupuncture at Hegu (LI 4), Xuehai (SP 10 ), Zusanli (ST 36) and Sanyinjiao (SP 6) combined with certirizine and the contr ol group (n=42) treated only by certirizine. The therapeutic effect and chan ges of serum complement C 3 content before and after treatment were observed. Results After treatment, the effective rate was 92 0% in the a cup uncture group and 73 6% in the control group with a significant difference betw een the two groups (P<0 05); the serum complement C 3 content before treatme nt in the patient of chronic urticaria was significantly lower than that in the healthy adult; there was a significant difference before and after treatment in complement C 3 content in the acupuncture group (P<0 05). Conclusion Acupuncture combined with certirizine is better than certirizine in the therapeutic effect and increases complement C 3 level in th e patient of urticaria.