2Bird AP.CpG-rich islands and the function of DNA methylation[J].Nature,1986,321(2):209.
3Gardiner-Garden M , Frommer M . CpG islands in vertebrate genomes[J].J Mol Biol,1987,196(1):261.
4Wutz A.Imprinted expression of the Igf2r gene depends on an intronic CpG island[J].Nature,1997,389(2):745.
5Issa JP.Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon[J].Nature Genet,1994,7(2):536.
6Issa JP,Vertino PM,Boehm CD.Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis[J].Proc Nat Acad Sc USA,1996,93(7):11757.
7Li LC , Chui C . Frequent methylation of estrogen receptor in prostate cancer:correlation with tumor progression[J].Cancer Res,2000,60(2):702.
8Razin A,Cedar H.DNA methylation and gene expression[J].Microbiol Rev,1991,55(2):451.
9Kass SU,Pruss D,Wolffe AP.How does DNA methylation repress transcription?[J].Trends Genet,1997,13(2):444.
2Momparler RL.Epigenetic therapy of cancer with 5-aza-2'-deoxycytidine (decitabine)[J].Seminars in Oncology,2005,32(5):443.
3Ginzinger DG.Gene quantification using real-time quantitative PCR:an emerging technology hits the mainstream[J].Exp Hematol,2002,30(6):503.
4Nelson WG,Yegnasubramanian S,Agoston AT,et al.Abnormal DNA methylation,epigenetics,and prostate cancer[J].Front Biosci,2007,12:4254.
5Kantarjian HM,O'Brien S,Cortes J,et al.Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia[J].Cancer,2003,98(3):522.
6Brueckner B,Kuck D,Lyko F.DNA methyltransferase inhibitors for cancer therapy[J].Cancer Journal,2007,13(1):17.
7Thibault A,Figg WD,Bergan RC,et al.A phase II study of 5-aza-2'deoxycytidine (decitabine) in hormone independent metastatic (D2) prostate cancer[J].Tumori,1998,84(1):87.
8Momparler RL,Ayoub J.Potential of 5-aza-2'-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer[J].Lung Cancer,2001,34 (Suppl 4):S111.
9Buchanan G,Irvine RA,Coetzee GA,et al.Contribution ofthe androgen receptor to prostate cancer predisposition and progression[J].Cancer Metastasis Reviews,2001,20(3-4):207.
10Chen CD,Welsbie DS,Tran C,et al.Molecular determinants of resistance to antiandrogen therapy[J].Nature Medicine,2004,10(1):33.