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心血管离子通道病的研究现状 被引量:5

Cardiovascular ion channel diseases
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摘要 心血管离子通道病是离子通道病的重要组成部分。作为原发或继发病因离子通道病变几乎参与了所有的心血管疾病的发生发展过程 ,是心脏性猝死的主要原因。本文对遗传性心脏离子通道病、获得性心脏离子通道病以及离子通道与血管疾病进行综述 ,并简要介绍了心血管离子通道病的治疗。 The cardiovascular ion channel disease is the main part among ion channel diseases.Abnormalities of ion channels are responsible mainly for sudden cardiac death and take part in occurrence and development of almost all cardiovascular diseases.What were reviewed are genetic and acquired cardiac ion channel diseases,and vascular diseases related with ion channels.Associated treatments are introduced briefly.
出处 《中华心律失常学杂志》 2004年第6期340-344,共5页 Chinese Journal of Cardiac Arrhythmias
基金 科技部国际合作项目 心血管离子通道病后基因组研究 (2 0 0 3DF0 0 0 0 3 7)
关键词 离子通道病 心血管疾病 心脏性猝死 治疗 获得性 发生发展 原发 血管疾病 研究现状 遗传性 Cardiovascular system Ion channel disease Arrhythmias Treatment
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  • 1Mohler PJ,Schott JJ,Gramolini AO,et al.Ankyrin-B mutation causes type 4 long QT cardiac arrhythmia and sudden cardiac death.Nature,2003,421:634-639.
  • 2Tan HL,Bezzina CR,Smith JP,et al.Genetic control of sodium channel function.Cardiovasc Res,2003,57:961-973.
  • 3Porres JM,Brugada J,Urbistondo V,et al.Fever unmasking the Brugada syndrome.PACE,2002,25:1 646-1 648.
  • 4Weiss R,Barmada MM,Nguyen T,et al.Clinical and molecular heterogeneity in the Brugada syndrome:a novel gene locus on chromosome 3. Circulation,2002,105:707-713.
  • 5Schott JJ,Alshinawi C,Kyndt F,et al.Cardiac conduction defects associate with mutations in SCN5A.Nat Genet,1999,23:20-21.
  • 6Tan HL,Bink-boelken MT,Bezzina CR,et al.A sodium channel mutation caused isolated cardiac conduction disease.Nature,2001,409:1 043-1 047.
  • 7Brugada R,Tapscott T,Grazyna Z.Identification of a genetic locus for familial atrial fibrillation.N Engl J Med,1997,336:905-911.
  • 8Chen YH,Xu SJ,Bendahhou S,et al.KCNQ1 gain-of-function mutation in familial atrial fibrillation.Science,2003,299:251-254.
  • 9Brugada R,Hong K,Dumaine R,et al.Sudden death associated with short QT syndrome linked to mutations in HERG.Circulation,2004,109:30-35.
  • 10Bellocq C,Van GA,Bezzina CR,et al.Mutation in the KCNQ1 gene leading to the short QT-interval syndrome.Circulation,2004,109:2 394-2 397.

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