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血管生长素促血管生成机制及其与疾病关系的研究进展 被引量：2

Progress of the angiogenic mechanism of the angiogenin and the relationship between angiogenin and diseases
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摘要 血管生长素 (angiogenin ,ANG)是一种促使新血管生成的诱导剂 ,它属于核糖核酸酶超家族中的一员。ANG蛋白含 12 3个氨基酸 ,相对分子量为 14 .4kD ,在肿瘤细胞中首先发现 ,也存在于正常细胞中 ,可由多种细胞分泌 ,其核糖核酸酶活性较弱。研究证实 ,ANG可以在细胞间及细胞内发挥促血管生长作用。ANG与缺血性疾病、肿瘤、及其它疾病的关系已见不少报道。
作者 程敏 郭淮莲
机构地区 北京大学人民医院神经内科
出处 《生理科学进展》 CAS CSCD 北大核心 2005年第1期55-57,共3页 Progress in Physiological Sciences
关键词 血管生长素 促血管生成 核糖核酸酶
分类号 R338 [医药卫生—人体生理学]
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参考文献10

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同被引文献16

  • 1张华,孙野青,张凤蕴,张大明,贾秀志,徐德昌,李春梅.模拟微重力对人脐静脉内皮细胞形态及NO产生的影响[J].航天医学与医学工程,2005,18(5):324-328. 被引量：5
  • 2杨月莲,刘宏,蔡德鸿.失重性骨量丢失治疗对策[J].中国骨质疏松杂志,2006,12(5):506-510. 被引量：2
  • 3张晓铀 汪恭质 丁柏.模拟失重对成骨细胞细胞周期影响的实验研究[J].中华航空航天医学杂志,1999,10(2):119-119.
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  • 7Hu GF, Riordan JF, Vallee BL. A putative Angiogenin receptor in Angiogenin-responsive human endothelial cells. Prol Natl Acad Sci USA, 1997, 94(6) : 2204-2209.
  • 8Shimoyama S, Shimizu N, Tsuji E, et al. Distribution of ANGiagenin and its gene message in colorectal cancer patients and their clinical relevance. Anticancer-Res 2002, 22(2B) :1045-1052.
  • 9Tsuji T, Sun Y, Kishimoto K, et al. Angiogenin Is Translocated to the Nucleus of HeLa Cells and Is Involved in Ribosomal RNA Transcription and Cell Proliferation. Cancer Res. 2005,65 ( 4 ) : 1352- 1360.
  • 10Yancy C W, Jessup M, Bozkurt B, et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. JAm Coll Cardiol. 2013, 62(16): e147-e239.

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生理科学进展
2005年 第1期

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