结核病初治涂阳经治2月不阴转78例分析

ANALYSIS OF 78 CASES NEW SMEAR POSITIVE TUBERCULOSES PATIENTS DON ’T TURNING NEGATIVE AT THE END OF 2 MONTH TREATMENT

目的 探讨广东省结核病控制项目初治涂阳肺结核治疗 2月末痰涂不阴转病人的临床特点 ,为提高化疗效果提供参考资料。方法 对项目实施初期所收治的初治涂阳肺结核治疗 2月末痰涂不阴转的 78病人的临床资料进行分析。结果 ①年龄≥ 6 0岁 15例 (19 2 % ) ;②合并糖尿病 16例 (2 0 5 % ) ;③平均就诊延误 12 2天 ;④病灶占 3个肺野以上 5 5例 (70 5 % ) ,有空洞 4 3例 (5 5 1% ) ,空洞≥ 2厘米 2 8例 ;⑤耐药16例 (2 0 5 % ) ,其中耐多药 4例 ;⑥治愈与完成疗程 5 5例 (70 5 % )。结论 就诊延误时间长 ,结核病病情重是初治涂阳肺结核化疗 2月末痰菌不阴转的主要原因 ,结核病防治工作需加强健康教育。

Objective To study the character of the smea r positive result at the end of 2 months treatment for new smear positive pulmonar y tuberculosis patients according to Tuberculosis Control Project in Guangdong P rovince and to provide the reference material for treatment. Methods The clinical data of 78 cases of the smear positive result at the end of 2 months treatment for new smear positive pulmonary tuberculosis patients from th e initial stage of the project was analyzed. Results ①The age of 15 cases over 60(19.2%);②16 cases with diabetes(20.5%);③The time of d elay seeking medical advice average 122 days;④55 cases with over 3 lung areas (70.5%), 43 cases with cavities in lungs (55.1%), 28 cases with over 2cm cavit ies in lungs. ⑤16 cases with drug resistance (20.5%), 4 cases with MDR TB. ⑥5 5 cases to be cured and completed the course of treatment (70.5%). Conc lusion The reason of the smear positive result at the end of 2 months t reatment new smear positive pulmonary tuberculosis patients is delay seeking med ical advice and heavy sickness, the health education need to be enhanced on tube rculosis control.