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骨再生与血管生成协同作用的分子机制 被引量：11

Molecular mechanism of synergism of angiogenesis and bone regeneration
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作者 段小军 杨柳 李起鸿
机构地区 第三军医大学西南医院关节外科中心
出处 《临床骨科杂志》 2005年第1期88-91,共4页 Journal of Clinical Orthopaedics
基金 国家自然科学基金资助项目(编号:30300079 30270375) 全军十五医药卫生科研重点基金资助项目(编号:01Z072)
关键词 骨再生 血管生成 协同作用 分子机制 生长因子 bone regeneration angiogenesis
分类号 R336 [医药卫生—人体生理学]
  • 相关文献

参考文献52

  • 1[1]Glowacki J. Angiogenesis in fracture repair[J]. Clin Orthop, 1998, ( 355S): 82～9.
  • 2[2]Gerber HP, Ferrara N. Angiogenesis and bone growth[J]. Trends Cardiovasc Med, 2000, 10(5): 223～8.
  • 3[3]Gerstenfeld LC, Cullinane DM, Barnes GL, et al. Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation[J]. J Cell Biochem, 2003,88(5): 873～84.
  • 4[4]Yoon ST, Boden SD. Osteoinductive molecules in orthopaedics: basic science and preclinical studies[J]. Clin Orthop, 2002,(395): 33～43.
  • 5[5]Abo-Auda W, Benza RL. Therapeutic angiogenesis: review of current concepts and future directions[J]. J Heart Lung Transplant, 2003, 22(4): 370～82.
  • 6卜丽佳,汪渊,任斌.血管新生与骨肿瘤发生及其治疗的分子机制[J].临床骨科杂志,2003,6(1):86-90. 被引量：2
  • 7[7]Ferrara N. Role of vascular endothelial growth factor in the regulation of angiogenesis[J]. Kidney Int, 1999, 56(3): 794～814.
  • 8[8]Zelzer E, McLean W, Ng YS, et al. Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis[J]. Development, 2002,129(8): 1893～904.
  • 9[9]Gerber HP, Vu TH, Ryan AM, et al. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation[J]. Nat Med, 1999, 5(6): 623～8.
  • 10[10]Street J, Winter D, Wang JH, et al. Is human fracture hematoma inherently angiogenic?[J]. Clin Orthop, 2000,(378): 224～37.

二级参考文献54

  • 1[1]Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases[J]. Nature, 2000;407(6801):249～257
  • 2[2]Yancopoulos GD, Davis S, Gale NW et al. Vascular-specific growth factors and blood vessel formation[J]. Nature,2000;407(6801):242～248
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  • 4[4]Holash J, Maisonpierre PC, Compton D et al. Vessel cooption, regression,and growth in tumors mediated by angiopoietins and VEGF[J]. Science, 1999;284(5422): 1994～ 1998
  • 5[5]Barinaga M. Angiogenesis research:cancer drugs found to work in new way[J]. Science, 2000;288(5464):245～250
  • 6[6]Gasparini G, Toi M, Biganzoli E et al. Thrombospondin-1 and -2 in node-negative breast cancer: correlation with angiogenic factors, p53, cathepsin D, hormone receptors and prognosis[J]. Oncology, 2001;60(1):72～80
  • 7[7]Senger DR. Molecular framework for angiogenesis:a complex web of interaction between extravasated plasma proteins and endothelial cell proteins induced by angiogenic cytokines[J]. Am J Pathol, 1996;149(1):1～7
  • 8[8]Pepper MS. Manipulating angiogenesis:from basic science to bedside[J]. Arterioscler Thromb Vasc Biol,1997;17(4):605～619
  • 9[9]Coffin JD, Harrison J, Schwartz S et al. Angioblast differentiation and morphogenesis of the vascular endothelial in the mouse embryo[J]. Dev Biol,1991;148(1):51～56
  • 10[10]Folkman J. Angiogenesis and angiogenesis inhibition: an overview[J]. EXS, 1997;79:1～8

共引文献42

同被引文献194

引证文献11

二级引证文献64

临床骨科杂志
2005年 第1期

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