3-(2'-氧代丁基)异苯并呋喃-1(3H)-酮的合成

Synthesis of-3-(2'–oxobutyl)isobenzofuran-1(3H)-one

通过邻甲酰苯甲酸在碱性条件与丁酮发生Claisen—Schmidt缩合反应,经酸化环合合成了3-(2'-氧代丁基)异苯并呋喃-1(3H)-酮。

formylbenzoic acid and butanone gave the Claisen-Schmidt condensation reaction in basic condition, which readily cyclizes on acidification to give 3-(2-oxobutyl)isobenzofuran-1(3H)-one.