N-(6-氯-3-甲基吡啶)乙胺合成条件的研究

Study on synthetic conditions of N-(6-chloro-3-methyl pyridyl) ethylamine

本文主要研究农药中间体N - (6 -氯 - 3-甲基吡啶 )乙胺的合成条件。研究了原料摩尔比(A)、反应温度 (B)、时间 (C)以及溶剂 (D)对产物收率的影响 ,得出较满意的结果 ,收率达 5 8. 89%。确定了n(2 -氯 - 5 -氯甲基吡啶 ) :n(乙胺 ) =1:4～ 5 ,取代反应温度为 2 0℃ ,反应时间为 2h的最佳合成条件。

In this paper, the process for producing N-(6-chloro-3-methylpyridyl)ethylamine was studied. The effect factors such as temperature, time, ratio of 2-chloro-5-chloro-methylpyridyl to ethylamine etc.were studied.The yield is more than 58.89%.The optimum synthetic conditions were ascertained.