症状性子宫肌瘤介入治疗的临床应用

Clinical application of interventional therapy for symptomatic uterine leiomyomas

目的:评价选择性子宫动脉栓塞术在症状性子宫肌瘤治疗中的临床效果。方法:对42例症状性子宫肌瘤患者采用Seldinger技术,经皮股动脉穿刺双侧子宫动脉插管栓塞治疗子宫肌瘤。结果:血管造影显示子宫肌瘤为富血管肿瘤,主要由双侧子宫动脉供血,栓塞治疗后子宫肌瘤血供被完全阻断,治疗1～6个月后随访结果表明:除11例肌瘤消失外,其余31例肌瘤均较治疗前明显缩小,6个月肌瘤体积平均缩小69.8%,临床症状明显改善。结论:选择性子宫动脉栓塞术是症状性子宫肌瘤的一种微创、有效、安全的治疗方法,具有重要的临床应用价值。

Objective To evaluate the clinical effectiveness of uterine arterioembolization in the treatment of symptomatic uterine leiomyomas. Methods Bilateral uterine arterioembolization via femoral artery with Seldinger technique were performed in 42 cases of symptomatic uterine leiomyomas. Results Arteriography showed that uterine leiomyomas’ blood supply mostly came from bilateral uterine arteries. After bilateral uterine arteries were embolized the blood supply of uterine leiomyomas were blocked completely. 1～6 months follow up study showed in 11 cases the leiomyomas disappeared entirely. By the end of the sixth month the mass of the other 31 cases decreased evidently and with an average shrinkage of 69.8% in volume. Clinical symptoms were improved obviously. Conclusions As a minimal invasive technique selective uterine arterioembolization is an effective and safe method for the treatment of symptomatic uterine leiomyomas and has important clinical value.