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药物遗传学与癌症治疗

Pharmacogenetics and Cancer Therapy
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摘要 药物遗传学为研究影响药物治疗结果的遗传学(基因)因素的学科。该文主要对药物遗传学与肿瘤药物治疗(包括药物治疗结果与毒副反应)、分子靶向治疗的关系进行综述。 Pharmacogenetics is a subject that studies genetic background influencing the therapeutic response.The relationship between pharmacogenetics and drug therapy(including treatment outcome and toxicity),and molecular target therapy of cancer are discussed in this review.
作者 胡胜 臧爱华
机构地区 湖北省肿瘤医院
出处 《中国肿瘤》 CAS 2005年第2期108-110,共3页 China Cancer
关键词 肿瘤 药物遗传学 药物疗法 neoplasms pharmacogenetics drug therapy
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参考文献11

  • 1Ulrich CM, Robien K, McLeod HL. Cancer pharmacogenetics: polymorphisms, pathways and beyond [J]. Nat Rev Cancer, 2003,3(12): 912-920.
  • 2Weinshilboum R. Inheritance and drug response [J]. N Engl J Med,2003,348 (6):529-537.
  • 3Relling MV,Dervieux T.Pharmacogenetics and cancer therapy [J].Nat Rev Cancer, 2001, 1 (2):99-108.
  • 4Marsh S, McLeod HL. Cancer pharmacogenetics [J]. Br J Cancer,2004,90(1): 8-11.
  • 5Desai AA, Innocenti F, Ratain MJ.Pharmacogenomics: road to anticancer therapeutics nirvana? [J].Oncogene, 2003,22(42): 6621-6628.
  • 6Nagasubramanian R, InnocentiF,Ratain MJ. Pharmacogenetics in cancer treatment [J]. Ann Rev Med,2003,54:437-452.
  • 7Dancey J, Sausville EA. Issues and progress with protein kinase inhibitors for cancer treatment [J]. Nat Rev Drug Discovery, 2003,2:296-313.
  • 8Liu W, Innocenti F, Chen P, et al.Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism [J]. Clin Cancer Res,2003, (3): 1009-1012.
  • 9Lynch TJ, Bell DW, Sordella R, et al.Activating mutations in the epidermal growth factor receptor underlying responsiveness of non -smallcell lung cancer to gefitinib [J]. N Engl J Med,2004,350(21): 2129-2139.
  • 10Paez JG, Janne PA, Lee JC, et al.EGFR mutations in lung cancer:correlation with clinical response to gefitinib therapy [J]. Science,2004,304(5676): 1497-1500.

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