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组织因子途径抑制物与缺血性脑血管病

Tissue Factor Pathway Inhibitor and Ischemic Cerebrovascular Diseases
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摘要 凝血系统在缺血性脑血管病的发生发展过程中发挥着重要作用。组织因子途径抑制物作为一 种生理性抗凝物质,即外源性凝血途径起始步骤的生理性抑制物,与缺血性脑血管病的关系密切。文 章重点介绍了组织因子途径抑制物在缺血性脑血管病中的变化、作用机制及其临床治疗前景。 Blood coagulation system plays an important role in the occurrence and development of ischemic cerebrovascular diseases. As a physiological anticoagulant, the tissue factor pathway inhibitor, namely the physiological inhibitor of the extrinsic coagulation pathway in the initial step is closely associated with ischemic cerebrovascular diseases. The paper mainly describes the changes of tissue factor pathway inhibitor, mechanisms of action and its clinical prospect in ischemic cerebrovascular diseases.
出处 《国外医学(脑血管疾病分册)》 2004年第12期925-927,共3页 Foreign Medical Sciences Cerebrovascular Diseases
基金 湖南省卫生厅资助项目(No.Y02-052)
关键词 缺血性脑血管病 组织因子途径抑制物 生理性 抗凝物质 发生发展 凝血系统 临床治疗 变化 tissue factor pathway inhibitor ■ ischemic cerebrovascular diseases ■ thrombosis
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