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萘普生和双氯芬酸止痛作用比较的随机对照试验 被引量:6

Comparison of analgesic effects between naproxen and diclofenac in randomized controlled trials
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摘要 萘普生2mL(0.2g)或双氯芬酸2mL(50mg)肌注于类风湿关节炎170例,bid,共14d,qd或bid于痛经女性70例及手术后疼痛72例作随机双盲试验。结果2药间止痛作用无显著差别(P>0.05)。在肌注处较强疼痛其萘普生组和双氯芬酸组分别为43%和42%。 Naproxen 2mL (0.2g) or diclofenac 2mL (50mg) was injected im to 170 patients with rheumatoid arthritis bid, for 14 d, and qd or bid to 70 women with dysmenorrhea and 72 patients with postoperative pain for randomized double-blind trials. Results showed no significant difference between the analgesic effects of the 2 drugs (P>0. 05). Severe pain at the im site was complained by 43% and 42% of the patients after naproxen and diclofenac, respectively.
出处 《新药与临床》 CSCD 北大核心 1993年第2期95-97,共3页
关键词 双氯芬酸 药理学 萘普生 rheumatoid arthritis/drug therapy postoperative pain/drug therapy dysmenorrhea/- drug therapy naproxen/therapeutic use diclofenac/therapeutic use randomized controlled trials
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