常用补气、健脾益气药药效作用的比较研究

The Comparative Study of Pharmacodynamicsof Chief Medicines of Strengthening Spleen Qi

用人参、黄芪、党参、白术、山药、大枣分别治疗因食醋造成脾气虚证的大鼠，各药均能改善脾虚症状，增加摄食量及自发活动，大便恢复正常，消除腹胀和胃肠炎变，增加粘液，升高血清Ｄ－木糖，增加小肠粘膜表面微绒毛和肠上皮细胞线粒体。但六药各具特点：人参补脾作用明显，提高免疫功能最优；党参功同人参而力弱，又能升高血清淀粉酶，黄芪作用不及参术，但有升高血清蛋白及血细胞的趋势；白术补脾作用明显，又能升高血清总蛋白；山药补脾功同参术，又能明显增加胃肠粘液；大枣补脾力弱．

o the rao model Of insufficiency of spleen Qi induced by oral adminstration of uinesar. we Studied whetherPanax ginseng. Astragalus memebranaceus,Codonopksis pilosula. Atractylodes macrocephala. Diaseorea opposita andZiziphus jujube have effects of strengthening spleen Qi in comparation with one another. The results showed that theyall could cure the symptom of insufficiency of spleen Qi Such as increasing ingestive and spontaneous action, resumingstool, ehiminating aodominal distention and inflammatory lesion of the gastrenteropathy. increasing neutral mucus. rising serum D-xylose, increasing microvilli of kjunal mucousa and mitochondria of iejnnal epithetal cells. But. their efects of strengthening spleen Qi have distinguishing feature. Panax ginseng is obvious in the effect of strengtheningspleen. It can enhance immunity. The effect of Codonopsis pilosuea is as well as Panax gingseng. Additionally it canrise serum amylases. Astragalus membranaleus is not as well as Panax gingseng, bot it has the trend of rising serumalbumen and increasing blood cells. Atractylodes macrocephala has the effect of strengthening spleen and increasingserum albumen. Dioscorea opposita is obvious in the effect of strengthening spleen and still can increase gastroentericmucus. While Zizighus jujuba is weak in strengthening spleen.