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GOODNESS-OF-FIT TEST WITH GENETIC BACKGROUND 被引量:1

GOODNESS-OF-FIT TEST WITH GENETIC BACKGROUND
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摘要 The chi-square test is a well-known goodness-of-fit test. It is available for arbitrary alternative hypothesis, particularly for a very general alternative. However, when the alternative is a “one-sided” hypothesis, which usually appears in genetic linkage analysis, the chi-square test does not use the information offered by the one-sided hypothesis.Therefore, it is possible that an appropriate one-sided test, which uses the information,will be better than the chi-square test. This paper gives such an efficient one-sided test.Monte Carlo simulation results show that it is more powerful than the chi-square test, and its power has been increased by 30 percent as compared with that of the chi-square test in most situations.
出处 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2005年第1期27-34,共8页 系统科学与复杂性学报(英文版)
关键词 chi-square test goodness-of-fit test monte carlo simulation 吻合度试验 χ 检验 蒙特卡罗模拟 遗传连锁分析
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  • 1Jane M Olson, John S Witte and Robert C. Elston, Tutorial in biostatistics genetic mapping of complex traits, Statist Med, 1999, 18: 2961-2981.
  • 2B K Suarez, J Rice and T Reich, The generalized sib pair IBD distribution: its use in the detection of linkage, Ann Hum Genet (Lond.), 1978, 42: 87-94.
  • 3Richard S Splielman, Ralph E McGinnis an(i Warren J. Ewens, Transmission test for linkage disequilibrium: The Insulin Gene Region and Insulin-dependent Diabetes Mellitus(IDDM), Am J Hum Genet, 1993, 52: 506-516.
  • 4N L Kaplan, E R Martin and B S Weir, Power studies for the transmission/disequilibrium tests with multiple alleles, Am J Hum Genet, 1997, 60: 691-702.
  • 5William C Blackwelder and Robert C Elson, A comparison of sibpajr linkage tests for disease susceptibility loci, Genetic Epidemiology, 1985, 2 : 85-97.
  • 6R N Cumow, A P Morris and J CI Whittaker, Locating genes involved in human diseases,Appl Statist., 1998, 47(Part 1): 63-76.
  • 7Jane M Olson, John S Witte and Robert C Elston, Tutorial in biostatistics genetic mapping of complex traits, Statist Med , 1999, 18: 2961-2981.
  • 8B K Suarez, J Rice and T Reich, The generalized sib pair IBD distribution: its use in the detection of linkage, Ann Hum Genet (Lond.), 1978, 42: 87-94.
  • 9Richard S Splielman, Ralph E McGinnis and Warren J Ewens, Transmission test for linkage disequilibrium: The Insulin Gene Region and Insulin-dependent Diabetes Mellitus(IDDM), Am J Hum Genet , 1993, 52: 506-516.
  • 10N L Kaplan, E R Martin and B S Weir, Power studies for the transmission/disequilibrium tests with multiple alleles, Am J Hum Genet , 1997, 60: 691-702.

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