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可溶性细胞黏附分子与动脉粥样硬化斑块不稳定关系的临床研究

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摘要 目的 探讨血清中可溶性黏附分子的水平与冠状动脉不稳定斑块的关系。方法 应用酶联免疫吸附法 (ELISA)检测 3 1例急性冠脉综合征 (ACS) (其中不稳定心绞痛 19例 ,急性心肌梗死 12例 )和 12例稳定性心绞痛患者及 10例正常对照组血清中的可溶性黏附分子sVCAM 1、sICAM 1的水平。结果 不稳定心绞痛、急性心肌梗死及稳定性心绞痛血清中VCAM 1和ICAM 1水平较对照组明显增高 ,与稳定性心绞痛相比较 ,不稳定性心绞痛患者血中的sVCAM 1和sICAM 1水平明显增高 ,具有显著性差异 ( P <0 .0 1) ,急性心肌梗死血清中水平较UA明显增高 ,具有显著性差异 (P <0 .0 1)。结论 急性冠脉综合征患者血清中sVCAM 1和sICAM 1均明显增高 ,sVCAM 1和sICAM
出处 《中原医刊》 2005年第1期1-2,共2页 Central Plains Medical Journal
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