摘要
目的 :了解倍美力软膏治疗萎缩性阴道炎的疗效及安全性。方法 :15 5例患者 7d内每晚阴道放入 1g倍美力软膏 ,7d后每周 1次 ,连用 8周。用药前后自身对照。结果 :用药后患者症状、体征得到改善(Р <0 .0 5 ) ,血清雌二醇 (E2 )明显升高 (P <0 .0 1)。用药后子宫内膜厚度等 6项安全性指标无显著性变化。结论 :该药安全、有效、方便 ,可广泛使用。
Objective: To determine the clinical ef fe ct of intravaginal premarin cream on atrophic vaginities and its side effects. Methods: 155 patients were received 1 gram intravaginal premar in cream(contains 0.625 mg premarin) per night. 1week later,drugs were given weekly and lasted 8 weeks. Auto-control was performed before and after drug adm inistration. Results: After drug application, the symptoms and signs of patients were improve(Р<0.05). Serum E 2 was significantly incre ased(Р<0.01). After drug application, 6 security parameters were not change d much. Conclusion: This drug is safe, effective and can be ap plied widely. [