摘要
用1∶1配比的病例对照研究和多因素分析相结合的方法,探讨了轻度精神发育迟滞的致病因素。分析表明,父母文化程度低、孕期情绪不良、孕期毒害因素、低出生体重、新生儿疾病、婴幼期严重疾病及精神病家族史是本病发生的危险因素。条件logistic回归揭示本病的前三位危险因素是婴幼期严重疾病、母亲文化程度低和精神病家族史。本结果为该病的综合防治提供了科学依据。
A case-control study was conducted in 1986 in 86 childrenwith mild mental retardation(MMR)at two special schools for mentalretarded in Jinan city and an equal number of controls matched with thecases for the year of birth,sex,and place of residence.The informationwas collectcd by interviewing the mothers.The following risk factorswere associated with the disease.They were poorer parents′education,distress and hazard factors during pregnancy,low birth weight,neonataldiseases,severe diseases in the first three years of life,and family historyof mental diseases,etc.The conditional logistic regression analysis showedthat the first three risk factors of MMR were severe diseases in the firstthree years of life,poorer monther′s education and family history ofmental diseases.The results provided some useful information for inter-vention and prevention of mild mental retardation.
出处
《山东医科大学学报》
1989年第1期30-33,共4页
Acta Academiae Medicinae Shandong
关键词
智力迟钝
回归分析
危险因素
儿童
Mental retardation
Risk factors
Comparative study
Regression analysis