摘要
安乃近是一种应用较广的解热镇痛药,其含量测定方法有碘量法和紫外分光光度法等。这些方法操作繁琐、分析周期长、专属性较差。制剂样品中的辅料、分解产物及水解产物等均会对测定产生干扰。本文基于安乃近的还原性,在氧化剂(碘酸钾)的作用下。
A new flow injection spectrophotometric method for the determination of analgin has been developed. The main factors which affect the determination were investigated. The absorption maximum is 650 nm. Under optimum conditions the calibration graph is linear in the range of 0. 2～3 mg/ml, the average recovery is 99. 8% with a relative standard deviation of 0. 5%. The proposed system permits the analysis of about 240 samples per hour and has the advantages of analytical efficiency, sensitivity and accuracy for the determination of analgin.
出处
《药学学报》
CAS
CSCD
北大核心
1993年第4期317-320,共4页
Acta Pharmaceutica Sinica
关键词
安乃近
分光光度法
Analgin
Flow injection analysis
Spectrophotometry
