摘要
本文以丙烯酸甲酯为原料，经过亲核取代、迈克尔加成、氯化环合三步反应合成２－甲基－异噻唑啉酮和５－氯－２－甲基－异噻唑啉酮。通过改变反应条件，初步探讨了反应温度、反应时间及反应物克分子配比等因素对产物收率的影响。
In thiz paper z-methyl-isothialin-3-one and 5-chloro-2methyl-isotheazolin-3-one are sythesized Staring from methyl acrylafe by the three Step reactions-nucleophillic substitution Michael addition and chlorination-cylizaation.The effects of reeactive temperature,reactive time and reactant mole guantity have been disscused on yied by varing reactive cconditions.
