中期胃癌36例病理学研究

A PATHOLOGIC STUDY ON GASTRIC CARCINOMA IN MODERATE PHASE

采用病理学方法，研究了３６例侵及肌层的胃癌（中期胃癌）。结果显示，本组中期胃癌中乳头状腺癌占２．８％，高分化管状腺癌占３０．５％，中分化管状腺癌占２５．０％，低分化腺癌占３０．５％，粘液腺癌占１１．１％。累及浅肌层者占４１．７％，累及深肌层者５８．３％。癌间质淋巴细胞中等量和大量浸润者分别为２７．８％和８．３％，癌间质纤维组织中等量和大量增生者分别为２２．２％和５．６％。胃周淋巴结转移率为４３．３％。术后平均生存时间为４．６±２．９年，５年生存率４７．８％，有淋巴结转移者５年生存率为３０．８％，无淋巴结转移者为６４．７％，淋巴结转移与否和病人的预后密切相关。简要讨论了中期胃癌的特点和意义。

A study on 36 cases of gastric carcinoma penetrating muscle(in moderate phase)was made by means of the pathologic methods.The results showed that the papillary adenocarcinoma, well differentiated tubular adenocarci- noma, moderately differentiated one, poorly differentiated one and mucous adenocarcinoma account for 2.8%,30.5%,25.0%,30.5%and 11.1%of the totalcases respectively.The carcinomas invaded the muscle's superficial partwere 41.7%of the 36 cases and 58.3% the deeper part.The lymphocytesinfiltration in the stroma was moderate in 27.8%and marked in 8.3%ofthese cases.The fibrosis of the stroma was moderate in 22.2%and markedin 5.6%of the group.The metastasis of peristomach lymph nodes tookplace in 43.3%of these cases.The duration of surival in postoperationwas 4.6±2.9 years in averaga.The 5-year-survival rates in the cases withmetastasis and non-metastasis were 30.8%and 64.7%respectively.A briefdiscussion was given on the feature and significance of gastric carcinomain moderate phase.