中西医结合治疗血栓闭塞性脉管炎临床及实验研究

CLINICAL AND EXPERIMENTAL STUDIES OF CNMBINED THERAPY OF CTM-WM ON THROMBOANGIITIS NBLITERAOS

对５５例血栓闭塞性脉管炎（ＴＡＯ）患者进行了血液流变学８项指标及甲皱微循环检测，并以健康者作对比观察。结果：①ＴＡＯ组多项流变学及甲皱微循环指标高于健康人组（ｐ＜０．０５），②ＴＡＯ临床分期之间其流变学各值亦有明显差别（Ｐ＜０．０５）；③治疗前后血液流变学及甲皱微循环各值亦存在明显差异（Ｐ＜０．０５）。总有效率９２．７％，截肢率为７．３％。表明血液流变学检测能反映临床病情轻重，可作为临床分期、中西医辨证分型的客观参考指标。血液流变学及甲皱微循环的检测为活血化瘀治疗、判定疗效及预后提供科学依据。

In this paper, eight hemorrheological indexesand nail fold microc r-culation of 55 cases thromboangiitis obliterans(TAO group)were examined and compared with normal group. The results were as follows:(1)Many hemorrheological indexes and microcirculatory indexes of the TAO group were higher than those of the normal group (P<0.05).(2 ) Hemorrhe-ological indexes were significant in various Phases of TAO (P<0.05).(3)hemorrheological indexes and nail fold microcirculation were different obviously before and after treatment (P<.05). The total effective rate was,927%;the amputatial rate was 7.3%.These data suggested that examina-tion of hemorrheological indexes and nail fold microcirculation was important in differentration of symptoms and signs in view of CTM,and also provided a scientific basisfor activating-blood and dissolving-stasis treatment.