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肝细胞增殖与肝癌发生研究进展

The progress on the researches of liver cell proliferation and hepatocarcinoma development
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摘要 肝癌的发生与肝细胞的凋亡和增殖调节失控有关。近年来的研究显示 ,肝癌的发生与肝细胞的增殖活性增强关系更大 ,肝细胞增殖活性的持续升高成为各种原因导致肝脏损害并最终发生肝癌的重要危险因素之一。对慢性肝病患者 ,肝组织细胞增殖情况的分析有助于肝癌高危人群的发现。
出处 《国外医学(肿瘤学分册)》 2003年第6期453-456,共4页 Foreign Medical Sciences (Cancer Section)
基金 国家自然科学基金资助项目 ( 3 0 0 70 847)
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参考文献18

  • 1Kitamura T, Watanabe S, Sato N. Liver regeneration, liver cancer and cyclines[J]. J Gastroenterol Hepatol, 1998,13(Suppl) :S96-99.
  • 2Major GN, Collier JD. Repair of DNA lesion O6-methylguanine in hepatocellular carcinogenesis [J]. J Hepatobiliary Pancreat Surg,1998,5 (4): 355-366.
  • 3Chuma M, Sakamoto M, Yamazaki K, et al. Expression profiling in multistage hepatocarcinogenesis: identification of HSP70 as a molecular marker of early hepatocellualr carcinoma [J]. Hepatology,2003,37( 1 ): 198-207.
  • 4Park Y, Chae KJ, Kim YB, et al. Apoptosis and proliferation in hepatocarcinogenesis related to cirrhoisis[J]. Cancer, 2001, 92(11): 2733-2738.
  • 5Chen GG, Lai PB, Chak EC, et al. Immunohistochemical analysis of pro-apoptotic Bid level in chronic hepatitis, hepatocellular carcinoma and liver metastases[J]. Cancer Lett, 2001,172(1): 75-82.
  • 6Pizem J, Marolt VF, Luzar B, et al. Proliferative and apoptotic activity in hepatocellular carcinoma and surrounding non-neopastic liver tissue[J]. Pflugers Arch, 2001,442(6 Suppl 1):R174-176.
  • 7Paiva C, Oshima CT, Lanzoni VP, et al. Apoptosis, PCNA and p53 in hepatocellular carcinoma[J]. Hepatogastroenterology, 2002,49(46): 1058-1061.
  • 8Yang S, Lin HZ, Hwang J, et al. Hepatic hyperplasia in noncirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition[J]. Cancer Res, 2001,61(13) :5016-5023.
  • 9Danato MF, Arosio E, Del Ninno E, et al. High rates of hepatocellular carcinoma in cirrhosis patients with high liver cell proliferation activity[J]. Hepatology, 2001,34(3) :523-528.
  • 10Shibata M, Morizane T, Uchida T, et al. Irregular regeneration of hepatocytss and risk of hepatocellular carcinoma in chronic hepatitis and cirrhosis with hepatitis-C-virus infection [J]. Lancet, 1998,351(9118): 1773-1777.

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