精神发育迟滞病因的Logistic回归分析

LOGISTIC REGRESSION ANALYSIS OF RISK FACTOR ON MENTAL RETAR—DATION

对太原市某培智学校100例精神发育迟滞(Mental retardation,MR)患儿进行1:2配比病例对照研究,使用条件Logistic回归模型进行多因素分析,24个因素中选出5个危险因素,分别为父母血缘关系,母孕期食绿叶菜少,儿童出生异常,儿童出生体重低、儿童中枢神经系统感染。并且母孕期食绿叶菜由多到少、儿童出生体重由高到低与患MR的相对危险性呈相反的剂量——反应关系。

With conditional logistic regression analysis, the risk factors of mental retardation (MR) were assessed in 100 MR children in the special schools and 200 controls in Taiyuan. The results of this 1: 2 matched case-control study showed that MR was significantly correlated with the following factors : family consanguinity, low intake of green vegetables during pregnancy, abnormal birth, low birth weight, the infection of the certral nervous system in the children. With decreasing intake of green vegetables and birth weight, there was significantly dose-response relationship for OR to them in MR children.